Born in Mountain Ash, Lee graduated from the University of Exeter with a first class honours degree and won the Cameron Mackintosh Foundation Scholarship to study at RADA.
He has played at the National Theatre several times, including Lysander in A Midsummer Night's Dream and in Peter Hall's the Bacchai. He appeared in the Fringe First-winning production of Jonathan Lichtenstein's The Pull of Negative Gravity at the Traverse, which subsequently transferred to New York. His theatre work in Wales includes Night Must Fall, Memory, Arcadia, Mary Stewart and Festen for Clwyd Theatr Cymru and Romeo & Juliet for Theatr Genedlaethol Cymru.
His screen credits include Love in a Cold Climate for the BBC and Caerdydd for S4C, which he has also directed.